PT - JOURNAL ARTICLE AU - Alokaily, Fahdah AU - AlKathiri, Reem AU - AlKathiri, Sarah AU - Alrashidi, Seham TI - A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine AID - 10.15537/smj.2022.43.1.20210914 DP - 2022 Jan 01 TA - Saudi Medical Journal PG - 105--107 VI - 43 IP - 1 4099 - http://smj.org.sa/content/43/1/105.short 4100 - http://smj.org.sa/content/43/1/105.full SO - Saudi Med J2022 Jan 01; 43 AB - This is a case report of a 31-year-old lady who is known to have ulcerative colitis for 15 years and was on mesalazine. She presented with periorbital swelling, sinusitis, epistaxis, and was found to have positive anti-neutrophil cytoplasmic antibody and anti-proteinase-3 of a high titer. Biopsy from the maxillary sinus showed chronic non-specific inflammation and biopsy from the periorbital fat revealed inflammation and granulomatous changes. She had no other organ involvement. She was diagnosed with a limited form of granumatosis and polyangiitis and treated with methotrexate and prednisolone. The symptoms disappeared after treatment.