RT Journal Article
SR Electronic
T1 Effect of bariatric surgery on cardiac function in obese patients
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 587
OP 591
DO 10.15537/smj.2022.6.20220136
VO 43
IS 6
A1 Mansur S. Alqunai
A1 Bandar S. Assakran
A1 Adel M. Widyan
A1 Annie Suresh
A1 Abdullah A. Alharbi
A1 Osamah I. Almosallam
A1 Abdullah H. Alromaih
A1 Abdulrahman H. Alashkar
A1 Daliyah F. Alotaibi
A1 Rami M. Abazid
YR 2022
UL http://smj.org.sa/content/43/6/587.abstract
AB Objectives: To analyze the clinical and echocardiographic changes in individuals with morbid obesity who underwent bariatric surgery.Methods: In total, 59 obese patients with body mass index >35 kg/m2 were prospectively enrolled. We assessed baseline pre-operative and a 6-month post-operative lipid profile, hemoglobin A1c, echocardiography, lifetime, and a 10-year risks of atherosclerotic disease for all patients.Results: The mean patients’ age was 37±12 years, with 40 (67.8%) women. We found that the pre-operative total cholesterol (4.2±1.1 vs. 4.4±1.1, p=0.014) and triglyceride levels (1.4±0.7 vs. 1.8±0.8, p<0.0001) were significantly lower than post-operative levels, while post-operative high-density lipoprotein levels were significantly higher (1.5±0.5 vs. 1.2±0.3, p<0.0001). The calculated 10-year risk of atherosclerotic cardiovascular disease was significantly lower post-operatively (1.1±1.6% vs. 1.6±1.8%, p<0.0001). Echocardiography follow-up revealed that diastolic dysfunction was more prevalent pre-operatively than that post-operatively (41% vs. 10%, p<0.0001). Post-operative left ventricular (LV) mass was significantly lesser than the pre-operative mass (168±252 g vs. 187±255 g, p=0.019), whereas the post-operative LV diastolic (46.5±7 mm vs. 38.5±18 mm, p=0.002) and systolic dimensions (31±5 mm vs. 25±11 mm, p=0.001) were significantly smaller.Conclusion: Bariatric surgery resulted in a significant amelioration in lipid profile, reduction in LV mass, and LV cavity dimensions.