RT Journal Article SR Electronic T1 COVID-19 in patients with end stage kidney disease at a large community hospital in Eastern Saudi Arabia. A prospective study JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 633 OP 636 DO 10.15537/smj.2022.43.6.20220003 VO 43 IS 6 A1 Ahmed M. Alkhunaizi A1 Hanaa Abd Elnabi A1 Abdulrazack Amir A1 Amber Anwar YR 2022 UL http://smj.org.sa/content/43/6/633.abstract AB Objectives: To report the outcome of patients with end stage kidney disease (ESKD) who were diagnosed with COVID-19 at a large community hospital in Eastern Saudi Arabia.Methods: A single center, prospective observational study at Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. Patients with ESKD who were maintained on dialysis and developed COVID-19 between June 15, 2020 and October 31, 2021 were enrolled.Results: In total, 30 patients with ESKD were diagnosed with severe acute respiratory syndrome coronavirus 2 infection. Twenty two (73%) patients developed the disease prior to COVID-19 vaccine rollout. The median age of the cohort was 63 (55-75) years. Most patients were diabetic (73%), hypertensive (97%) and had a median body mass index of 28 kg/m2. Twenty seven (90%) patients required admission, 16 (52%) patients developed pneumonia, and 5 (17%) patients required mechanical ventilation. Patients who developed pneumonia were older, and the majority had diabetes mellitus and coronary artery disease. Five patients died with a total mortality of 17%.Conclusion: Patients with ESKD who developed COVID-19 had a poor outcome with high mortality compared to the general population. Presence of diabetes mellitus, coronary artery disease and older age were associated with a higher risk of severe disease. There was a sharp decline in the number of positive cases following implementation of the vaccination program.