PT - JOURNAL ARTICLE AU - Köksal, Bengü G. AU - Küçükosman, Gamze AU - Özcan, Pişkin AU - Baytar, Çağdaş AU - Bollucuoğlu, Keziban AU - Okyay, Rahşan D. AU - Ayoğlu, Hilal TI - Effects of different fresh gas flows on carboxyhemoglobin levels: non-invasive carbon monoxide monitoring AID - 10.15537/smj.2022.43.8.20220424 DP - 2022 Aug 01 TA - Saudi Medical Journal PG - 891--898 VI - 43 IP - 8 4099 - http://smj.org.sa/content/43/8/891.short 4100 - http://smj.org.sa/content/43/8/891.full SO - Saudi Med J2022 Aug 01; 43 AB - Objectives: To observe the effect of different fresh gas flows (FGF) on carboxyhemoglobin (COHb) levels non-invasively and continuously and to determine the contribution of the smoking status to intraoperative carbon monoxide (CO) accumulation and respiratory complications.Methods: A total of 64 patients were included in the study. Carboxyhemoglobin level was monitored non-invasively from the fingertip. Patients were divided into 2 according to the FGF as low-flow anesthesia (LFA; Group L) and high flow anesthesia (Group H). Each group was divided again into 2 groups as smokers and non-smokers. Carboxyhemoglobin and and the respiratory complications that occurred in the post-anesthesia care unit were recorded.Results: The mean COHb values were significantly higher in Group L between 30th and 210th minutes. Furthermore, in Group L, intraoperative COHb levels were significantly higher in smokers compared to non-smokers in all periods. In group H, no difference was observed between smokers and non-smokers in terms of COHb levels after 60 minutes and also preoperative COHb levels of the patients developed respiratory complication was higher.Conclusion: If the CO2 absorbent is properly preserved in patients who are administered LFA, there will be no risk of CO accumulation even in chronic smokers.ClinicalTrials.gov REG. No.: NCT04832256