RT Journal Article SR Electronic T1 Cardiac myxoma presenting with multisystem involvement JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1057 OP 1061 DO 10.15537/smj.2022.43.9.20220346 VO 43 IS 9 A1 Ghofran A. Ageely A1 Salhah S. Alsulami A1 Ahad A. Alkenani A1 Ebtihal EMS. Albeshri YR 2022 UL http://smj.org.sa/content/43/9/1057.abstract AB A cardiac myxoma is a rare tumor that could be incidental or present with common symptoms due to embolization. A minority of cases are attributed to carney complex, a rare inherited disease. A 73-year-old Asian male presented with acute left-side weakness, slurred speech, gait imbalance, and subacute constitutional symptoms. Left atrial myxoma was discovered by computed tomography and confirmed by echocardiography. Brain imaging revealed pituitary macroadenoma with subarachnoid and intraventricular hemorrages. The hormonal profile confirmed pituitary apoplexy, for which hormone replacement was initiated. Workup also revealed multiple endocrine tumors and excluded infection and malignancy. Myxoma resection could not be carried out, due to the patient’s rapid clinical deterioration and death.Furthermore, the presence of cardiac myxoma, non-functioning pituitary macroadenomas, and pituitary apoplexy is extremely rare and rarely documented in the literature. Therefore, we emphasize clinical awareness of rare conditions with atypical presentations to improve outcomes.