PT  - JOURNAL ARTICLE
AU  - Aldali, Jehad A.
AU  - Alotaibi, Fahad T.
AU  - Alasiri, Glowi A.
AU  - Almesned, Renad A.
AU  - Alromih, Aroob M.
AU  - Almohandes, Afnan M.
AU  - Alsenidi, Shahad F.
TI  - Evaluate the side effect associated with COVID-19 vaccine on adolescents in Riyadh, Saudi Arabia
AID  - 10.15537/smj.2022.43.11.20220493
DP  - 2022 Nov 01
TA  - Saudi Medical Journal
PG  - 1248--1253
VI  - 43
IP  - 11
4099  - http://smj.org.sa/content/43/11/1248.short
4100  - http://smj.org.sa/content/43/11/1248.full
SO  - Saudi Med J2022 Nov 01; 43
AB  - Objectives: To investigate the side effects of Pizer- BioNTech mRNA (BNT162b2) and Spikevax (mRNA- 1273) Coronavirus disease 2019 (COVID-19) vaccines on adolescents in Riyadh, Saudi Arabia.Methods: A cross-sectional study using an online questionnaire was carried out among COVID-19 vaccine adolescent recipients in Riyadh, Saudi Arabia. After receiving at least one dose of each vaccine, general and demographic data were collected, and vaccine-related side effects were evaluated.Results: The final sample consisted of 604 participants with a majority age group of 16-17 years old. Approximately 89.1% of the study participants were female. Most participants reported pain at the injection site (85.1% 1st dose, 79.8% 2nd dose), feeling tired, and headache (58.6% 1st dose, 64.2% 2nd dose). Moreover, we found that patients who took the first dose and had a chronic disease had 2.4 times higher odds of having menstrual disorder (females) than non-chronic disease patients (p=0.03) and 4.5 times higher odds of exhibiting breathing congestion (p=0.01). In addition, patients with chronic disease had 2.4 times higher odds of exhibiting muscle and joint pain and dizziness than non-chronic disease patients (p=0.01, p=0.02). Males were less likely to have dizziness after the first dose than females (OR=0.26, p=0.01).Conclusion: This study investigates the adverse effects of COVID-19 vaccines among adolescents in Riyadh. As a result, this study creates a database to inform people about the risk of experiencing side effects based on their gender, age, and the vaccine type; more investigation is needed to better understand the link between risk factors and the development of adverse effects.