@article {Sindi67, author = {Anees A. Sindi and Wail A. Tashkandi and Mohammed W. Jastaniah and Mohammed A. Bashanfar and Ahmed F. Fakhri and Fahad S. Alsallum and Hamdan B. Alguydi and Alyaa Elhazmi and Talal A. Al-Khatib and Maha M. Alawi and Ibrahim Abushoshah}, title = {Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19}, volume = {44}, number = {1}, pages = {67--73}, year = {2023}, doi = {10.15537/smj.2023.44.1.20220462}, publisher = {Saudi Medical Journal}, abstract = {Objectives: To describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection.Methods: We carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertiary hospital in Jeddah, Saudi Arabia, from April 2020 to December 2020. Electronic medical records were reviewed for demographics, clinical status, hospital course, and outcome; and they were compared between the patients with or without DM.Results: Out of 198 patients included in the study, 86 (43.4\%) were diabetic and 112 (56.5\%) were non-diabetic. Majority of the patients were males 139 (70.2\%) with a mean age of 54.14{\textpm}14.89 years. In-hospital mortality rate was higher in diabetic patients than in non-diabetic patients (40 vs. 32; p=0.011). The most common comorbidity was hypertension (n=95, 48\%) followed by ischemic heart disease (n=35, 17.7\%), chronic kidney disease (n=17, 9.6\%), and bronchial asthma (n=10, 5.1\%).Conclusion: The risk of SARS-CoV-2 infection is higher among diabetic patients; particularly, those with preexisting co-morbidities or geriatric patients. Diabetic patients are prone to a severe clinical course of COVID-19 and a significantly higher mortality rate.}, issn = {0379-5284}, URL = {https://smj.org.sa/content/44/1/67}, eprint = {https://smj.org.sa/content/44/1/67.full.pdf}, journal = {Saudi Medical Journal} }