TY - JOUR T1 - A prospective double-blinded randomized control trial comparing erector spinae plane block to thoracic epidural analgesia for postoperative pain in video-assisted thoracic surgery JF - Saudi Medical Journal JO - Saudi Med J SP - 155 LP - 163 DO - 10.15537/smj.2023.44.2.20220644 VL - 44 IS - 2 AU - Jeong-Min Hong AU - Eunsoo Kim AU - Soeun Jeon AU - Dowon Lee AU - Jiseok Baik AU - Ah-Reum Cho AU - Jeong Su Cho AU - Hyo Yeong Ahn Y1 - 2023/02/01 UR - http://smj.org.sa/content/44/2/155.abstract N2 - Objectives: To compare the analgesic efficacies of erector spinae plane (ESP) block and thoracic epidural analgesia (TEA) in video-assisted thoracic surgery (VATS).Methods: Sixty patients undergoing VATS received patient-controlled TEA with a basal rate of 3 ml/hour (h), a bolus of 3 ml (Group E), or ESP block with programmed intermittent bolus infusions of 15 mL/3 h and a bolus of 5 ml (Group ES) for 2 postoperative days. The primary outcome was to compare pain scores at rest 24 h postoperatively between the 2 groups. Secondary outcomes included NRS score for 48 h, procedural time, dermatomal spread, use of rescue medication, adverse events, and patient satisfaction.Results: Patients with continuous ESP block had a higher NRS score than those with TEA but no statistical difference at a specific time. The dermatomal spread was more extensive in the TEA group than in the ESP block group (p=0.016); cumulative morphine consumption was higher in the ESP block group (p=0.047). The incidence of overall adverse events in the TEA group was higher than in the ESP block group (p=0.045).Conclusion: Erector spinae plane block may be inferior to TEA for analgesia following VATS, but it could have tolerable analgesia and a better side effect profile than TEA. Therefore, it could be an alternative to TEA as a component of multimodal analgesia. ER -