PT  - JOURNAL ARTICLE
AU  - Akgül, Fethiye
AU  - Tüzer, Can
AU  - Arslan, Yusuf
AU  - Sevim, Bünyamin
TI  - COVID-19 infection during pregnancy
AID  - 10.15537/smj.2023.44.3.20220729
DP  - 2023 Mar 01
TA  - Saudi Medical Journal
PG  - 268--276
VI  - 44
IP  - 3
4099  - http://smj.org.sa/content/44/3/268.short
4100  - http://smj.org.sa/content/44/3/268.full
SO  - Saudi Med J2023 Mar 01; 44
AB  - Objectives: To evaluate the maternal and fetal clinical outcomes in SARS-CoV-2 infected pregnant women during the whole period of the pandemic in a single province in the southeast of Turkey.Methods: This retrospective study included patients who were screened from the medical registration system and found to be infected with SARS-CoV-2 virus during pregnancy. The demographic, clinical, laboratory, and radiological features of all the patients were obtained and compared between groups classified as severe-critical and mild-moderate disease severity.Results: The mean age of all the cases was 29.0±5.3 years in the mild-moderate cases, and 30.1±5.5 years in the severe-critical cases. The rates of 3rd trimester, cesarean and premature birth, high body mass index (BMI), symptoms of cough and dyspnea, the presence of comorbidities, and hypothyroidism were significantly higher in the severe-critical cases than in the mild-moderate group. In the univariate analyses, BMI, dyspnea, cough, maternal complication rate, the neutrophil/lymphocyte ratio, the values of white blood cells, procalcitonin, high-sensitive C-reactive protein, D-dimer, ferritin, aspartate aminotransferase, and alanine aminotransferase were detected as significant risk factors. In the multivariate analysis, only procalcitonin was a significant factor.Conclusion: In the 3rd trimester of pregnancy, obesity and hypothyroidism were found to be risk factors for severe-critical cases of COVID-19 infection, and the clinical course was more severe with a higher rate of mortality in the recent period of the pandemic.