RT Journal Article
SR Electronic
T1 Factors influencing blood pressure fluctuation in pediatric patients with sickle cell disease in Saudi Arabia
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 655
OP 660
DO 10.15537/smj.2023.44.7.20230251
VO 44
IS 7
A1 Bahaidarah, Saud
A1 Alzahrani, Fatma
A1 Alshinqiti, Mohammed
A1 Moria, Nader
A1 Alahwal, Fahad
A1 Naghi, Khalid
A1 Abdulfattah, Ammar
A1 Alharbi, Mohammed
A1 Abdelmohsen, Gaser
YR 2023
UL http://smj.org.sa/content/44/7/655.abstract
AB Objectives: To investigate changes in blood pressure (BP) among pediatric patients with sickle cell disease (SCD) and determine the variables that might influence these changes.Methods: A total of 100 pediatric patients with SCD who followed up in the pediatric outpatient clinic were recruited for this retrospective cohort study. Clinical data included anthropometric measures, average systolic and diastolic BP recorded during multiple follow-up visits, hemoglobin (Hb) level, serum creatinine, and hemoglobin S percentage. Blood pressure measurements were categorized according to the guidelines of the American Academy of Pediatrics (AAP, 2017).Results: In this cohort, 68% of the patients had normal systolic BP, 13% had elevated systolic BP, 17% had stage 1 hypertension (HTN), while only 2% reported stage 2 HTN. Patients who were overweight had relatively high systolic BP compared to patients who were underweight (p=0.034) or had normal weight (p=0.023). The average systolic BP significantly correlates with body mass index (r= 0.377, p<0.001) and serum creatinine (r=0.369, p<0.001).Conclusion: Pediatric overweight SCD patients exhibited higher average systolic BP than those underweight or normal weight. Body mass index and serum creatinine significantly influenced the average systolic BP more than the Hb level or Hb S percentage.