PT - JOURNAL ARTICLE AU - Sadiqa, Ayesha AU - Khalid, Ambreen AU - Islam, Abdullah TI - Physiological association of the breakpoint with the duration of hyperventilation AID - 10.15537/smj.2023.44.10.20230358 DP - 2023 Oct 01 TA - Saudi Medical Journal PG - 995--999 VI - 44 IP - 10 4099 - http://smj.org.sa/content/44/10/995.short 4100 - http://smj.org.sa/content/44/10/995.full SO - Saudi Med J2023 Oct 01; 44 AB - Objectives: To determine the relationship of body mass index (BMI) with breath-holding time (BHT) as well as that of BHT with the duration of hyperventilation (DOH) in young healthy adults.Methods: An observational study was performed at Shalamar Medical and Dental College, Lahore, Pakistan, between May 2021 and June 2022. Healthy first-year Bachelor of Medicine, Bachelor of Surgery students aged 18-22 years, with a normal BMI were included. Spirometric measurements were taken through a spirometer pod connected to a pneumotachometer (model: Power Lab 26T). Body mass index was calculated as the weight (kg) to height (m2) ratio. Pearson correlation, linear regression, and t tests were applied using SPSS.Results: A total of 101 subjects participated, comprising of 44 men and 57 women. A weak negative association was found between BMI and BHT in all subjects (r= −0.08, p=0.34), in men (r= −0.24, p=0.11), and in women (r= −0.092, p=0.497). Furthermore, a strong association was observed between BHT and DOH in all subjects (r=0.64, p=0.000), in men (r=0.604, p=0.000), and in women (r=0.518, p=0.000). Moreover, a nonsignificant weak inverse linear regression was found between the BMI and BHT of all subjects (β= −0.087, p=0.38), of men (β= −0.241, p=0.11), and of women (β= −0.092, p=0.49). Lastly, a significantly strong positive regression was observed between the BHT and DOH of all subjects (β=0.637, p=0.000), of men (β=0.604, p=0.000), and of women (β=0.518, p=0.000).Conclusion: No association was found between BMI and BHT. A strong positive association was observed between BHT and DOH in all healthy young people.