RT Journal Article SR Electronic T1 Physiological association of the breakpoint with the duration of hyperventilation JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 995 OP 999 DO 10.15537/smj.2023.44.10.20230358 VO 44 IS 10 A1 Sadiqa, Ayesha A1 Khalid, Ambreen A1 Islam, Abdullah YR 2023 UL http://smj.org.sa/content/44/10/995.abstract AB Objectives: To determine the relationship of body mass index (BMI) with breath-holding time (BHT) as well as that of BHT with the duration of hyperventilation (DOH) in young healthy adults.Methods: An observational study was performed at Shalamar Medical and Dental College, Lahore, Pakistan, between May 2021 and June 2022. Healthy first-year Bachelor of Medicine, Bachelor of Surgery students aged 18-22 years, with a normal BMI were included. Spirometric measurements were taken through a spirometer pod connected to a pneumotachometer (model: Power Lab 26T). Body mass index was calculated as the weight (kg) to height (m2) ratio. Pearson correlation, linear regression, and t tests were applied using SPSS.Results: A total of 101 subjects participated, comprising of 44 men and 57 women. A weak negative association was found between BMI and BHT in all subjects (r= −0.08, p=0.34), in men (r= −0.24, p=0.11), and in women (r= −0.092, p=0.497). Furthermore, a strong association was observed between BHT and DOH in all subjects (r=0.64, p=0.000), in men (r=0.604, p=0.000), and in women (r=0.518, p=0.000). Moreover, a nonsignificant weak inverse linear regression was found between the BMI and BHT of all subjects (β= −0.087, p=0.38), of men (β= −0.241, p=0.11), and of women (β= −0.092, p=0.49). Lastly, a significantly strong positive regression was observed between the BHT and DOH of all subjects (β=0.637, p=0.000), of men (β=0.604, p=0.000), and of women (β=0.518, p=0.000).Conclusion: No association was found between BMI and BHT. A strong positive association was observed between BHT and DOH in all healthy young people.