PT  - JOURNAL ARTICLE
AU  - Polat, Sanem Eryilmaz
AU  - Uytun, Salih
AU  - Bilgiç, Işıl
AU  - Tuğcu, Gokcen D.
TI  - Macrophage activation syndrome induced by <em>Staphylococcus Epidermidis</em> in a pediatric patient with cystic fibrosis and familial Mediterranean fever
AID  - 10.15537/smj.2023.44.10.20230201
DP  - 2023 Oct 01
TA  - Saudi Medical Journal
PG  - 1061--1064
VI  - 44
IP  - 10
4099  - http://smj.org.sa/content/44/10/1061.short
4100  - http://smj.org.sa/content/44/10/1061.full
SO  - Saudi Med J2023 Oct 01; 44
AB  - Staphylococcus epidermidis (S. epidermidis) is the most frequently isolated member of the coagulase-negative staphylococci, which colonizes the skin and mucous membranes of the human body. Despite being a component of the normal flora, S. epidermidis can act as an opportunistic pathogen and is frequently implicated in both bacterial and nosocomial infections. Macrophage activation syndrome (MAS) is a rare but potentially fatal disease that occurs as a result of increased activation and proliferation of T lymphocytes and macrophages in response to infections and immune mediated diseases. It is very rare in patients with cystic fibrosis. Here we report a case of an 8-year-old girl with cystic fibrosis and familial Mediterranean fever who developed MAS after contracting a S. epidermidis infection.