RT Journal Article SR Electronic T1 Olfactory dysfunction among patients with COVID-19 JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1085 OP 1103 DO 10.15537/smj.2023.44.11.20230264 VO 44 IS 11 A1 Feras M. Alkholaiwi A1 Alhanouf F. Altamimi A1 Hanan H. Almalki A1 Fay A. Almughaiseeb A1 Shoug S. Alsubaie A1 Hessah S. Alsayahi A1 Fras W. Alhijli A1 Reema S. Alobaishi A1 Amit Agrawal A1 Zuhour A. Alqahtani A1 Fahad Z. Alotaibi YR 2023 UL http://smj.org.sa/content/44/11/1085.abstract AB Objectives: To assess the frequency of olfactory dysfunction (OD) among individuals afflicted with coronavirus disease of 2019 (COVID-19).Methods: A comprehensive literature search was carried out across several bibliographical databases (PubMed, Scopus, Google Scholar, and Web of Science) to extract publications in the English language between January 2020 and December 2021 to report the incidence of OD alone or together with gustatory dysfunction (GD) among COVID-19 patients.Results: Based on eligibility criteria, 84 articles were included from 27 countries, comprising 36,903 patients, of whom 58.1% were females. The generality rates of olfactory impairment alone was 34.60% and in conjunction with GD was 11.36%. Patients with OD were subclassified into various categories, and the prevalence of anosmia was 20.85%, 5.04% for hyposmia, 8.88% for anosmia or hyposmia, 1.84% for parosmia, 0.78% for phantosmia, and 0.02% for hyperosmia, among COVID-19 patients.Conclusion: Clinical features associated with OD, either isolated or in combination with GD, are common in patients with COVID-19 and consider important signs of COVID-19 that may guide clinicians in the early phase of the disease.PROSPERO Reg. No.: 417296