RT Journal Article SR Electronic T1 Outcomes and appropriateness of colonoscopy referrals at King Khalid University Hospital, Saudi Arabia JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1167 OP 1173 DO 10.15537/smj.2023.44.11.20230378 VO 44 IS 11 A1 AlQahtani, Shahad M. A1 Alshammari, Sulaiman A. A1 Khidir, Reem J. A1 AlKhunaizi, Maha F. A1 Abdulqader, Osama M. YR 2023 UL http://smj.org.sa/content/44/11/1167.abstract AB Objectives: To examine the colonoscopy referrals in an open-access system and determine the outcome and factors associated with appropriate referral.Methods: A retrospective study of colonoscopy referrals used patients’ medical records at King Khalid University Hospital, Riyadh, Saudi Arabia, during 2020-2022. Fisher’s exact or Pearson’s Chi-squared test were used for data analysis.Results: Out of 365 patients, 95.1% were referred from family medicine clinics with a mean age of 56.2±15.7 years. Men account for 53.2% of patients. The most common symptoms were change in bowel habits (35.6%), abdominal pain (30.4%), and anemia (20.1%). A family history of colorectal cancer was positive in 12.1%, while a personal history was positive in 4.4%. Most referrals (86.0%) were appropriate based on the American Society for Gastrointestinal Endoscopy (ASGE) guidelines. However, approximately 89.1% of patients aged ≥45 years had neoplasia and 40.0% had inflammatory bowel disease (p=0.019). The rank of the physicians (p=0.558) or the gender of the patients (p=0.665) did not influence the appropriateness. The inappropriate referrals were lower in patients with neoplasia (1.6%) than in patients with other lesions (p=0.002).Conclusion: The colonoscopy referrals were appropriate. The incidence of neoplasia was higher among those aged ≥45. Low inappropriate referrals and a high neoplasia detection were found based on ASGE guidelines. Future research should involve prospective multicenter referrals from family physicians outside hospitals and investigate patients’ hesitancy to proceed with colonoscopy and cost-effectiveness.