PT  - JOURNAL ARTICLE
AU  - Mete, Ayşe Ö.
AU  - Karaoğlan, İlkay
AU  - Koçak, Kübra
AU  - Şahin, Begüm
AU  - Yaşamali, Elif
AU  - Kilisli, Ali E.
AU  - Uyar, Meral
TI  - Causes of sleep disturbance in human immunodeficiency virus-infected individuals
AID  - 10.15537/smj.2023.44.12.20230390
DP  - 2023 Dec 01
TA  - Saudi Medical Journal
PG  - 1248--1253
VI  - 44
IP  - 12
4099  - http://smj.org.sa/content/44/12/1248.short
4100  - http://smj.org.sa/content/44/12/1248.full
SO  - Saudi Med J2023 Dec 01; 44
AB  - Objectives: To examine the possible association of obstructive sleep apnea (OSA) and depression on sleep quality in people living with human immunodeficiency virus (PWLHIV).Methods: Adult PWLHIV were included in this prospective, cross-sectional, case-control study. Our study was completed with 99 patients and 80 control subjects. To investigate sleep quality, the Pittsburgh Sleep Quality Scale and Stanford Sleepiness Scale were used; to determine the risk of OSA, the Berlin and STOP-BANG questionnaires were used; and to evaluate the existence and degree of depression, the Beck Depression Inventory was applied.Results: Patients had significantly higher daytime sleepiness (p=0.002) and absent-mindedness (p=0.004). The rate of being able to concentrate on one’s work was significantly higher in the control group compared with the patient group (p=0.000). More participants in the patient group had poor sleep quality (57% versus [vs.] 47.5%). The sleep quality score was significantly higher in the patient group (6.32 vs 5.23; p=0.032). Daytime dysfunction was significantly higher in the patient group (p=0.004). The rate of OSA risk was similar between the patient group and the control group on both the Berlin and STOP-BANG questionnaires (p=0.443 and p=0.581). Rates and numbers of depression the patient group were significantly higher (p=0.007).Conclusion: The results suggest that depression may be the most likely cause of sleep disorders in PWLHIV, regardless of OSA.