PT  - JOURNAL ARTICLE
AU  - Wang, Kai
AU  - Zeng, Deli
AU  - Chen, Zijun
AU  - Yu, Wei
TI  - Impact of left atrial diameter on all-cause mortality of patients with STEMI undergoing primary percutaneous coronary intervention
AID  - 10.15537/smj.2023.44.12.20230235
DP  - 2023 Dec 01
TA  - Saudi Medical Journal
PG  - 1260--1268
VI  - 44
IP  - 12
4099  - http://smj.org.sa/content/44/12/1260.short
4100  - http://smj.org.sa/content/44/12/1260.full
SO  - Saudi Med J2023 Dec 01; 44
AB  - Objectives: To evaluating the predictive significance of the left atrial diameter in acute ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI).Methods: The STEMI population came from 2 retrospective cohorts with 1097 patients, cohorts A (YongChuan Hospital) and cohorts B (Taizhou First People’s Hospital). Within 3 days (cohort A) or 5 days (cohort B) post-PCI, patients underwent ultrasound evaluations. Cohort A was segmented into quartile categories based on eft atrial diameter (LAd) (Q1 to Q4). The odds ratios (ORs) for overall mortality were assessed using logistic regression. Cohort B was used for sensitivity analysis.Results: During follow-up period, 226 (20.6%) patients experienced endpoint. In cohort A, univariable odds ratios were 2.68 (95%CI 1.11~6.89), 5.32 (95%CI 2.46~12.83) and 11.92 (95%CI 5.78~27.92), while multivariate ORs were 2.25 (95%CI 0.82~6.55), 5.09 (95%CI 2.12~13.56), and 15.05 (95%CI 6.58~39.09) in Q2 to Q4 group, respectively, compared with Q1 group (p for trend <0.001). Upon subgroup evaluation, the correlation between LAd and the likelihood of overall mortality was more pronounced in patients having a left ventricular ejection fraction (LVEF) between 40% and 50%, and those with LVEF ≥50%, in contrast to those with LVEF <40% (p for interaction <0.001).Conclusion: Left atrial diameter is indicative of the long-term overall mortality risk in STEMI patients post-PCI, particularly in those with an LVEF ≥ 40%.