RT Journal Article
SR Electronic
T1 The impact of sinusitis on dose distribution in a radiotherapy plan by in silico study
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 235
OP 240
DO 10.15537/smj.2024.45.3.20230520
VO 45
IS 3
A1 Hanan M. Alzahrani
YR 2024
UL http://smj.org.sa/content/45/3/235.abstract
AB Objectives: To assess the impact of changes in sinus aeration on dose variation in nasopharyngeal cases using a single beam with various field sizes and real patient computed tomography (CT) images.Methods: The calculations were carried out on a computer equipped with an Intel Xeon (R) Gold 5118 processor operating at 2.30 GHz in 2022 at Taibah University, Al Madinah Al Munawwarah for a retrospective nasopharyngeal case. At the patient level, the impact on dose distribution was examined for different field sizes by comparing the percentage depth dose. The dose discrepancy was evaluated by comparing the dose delivered without considering the anatomical changes observed in the initial fraction to the dose adjusted to account for these changes using a 2D gamma analysis. With a criterion of 1% dose difference and 1 mm distance to agreement, the gamma level for analysis was set at 95%.Results: The study findings indicated that the observed effect diminished by approximately 50% for both 5 cm x 5 cm and 10 cm x 10 cm field sizes compared to the 3 cm x 3 cm size, where there was an overlap between the planning target volume and sinusitis.Conclusion: The study concluded that the impact of dose discrepancy was more pronounced in smaller field sizes.