PT - JOURNAL ARTICLE AU - Li, Fuxing AU - Zhu, Junqi AU - Zheng, Yunwei AU - Fang, Youling AU - Hu, Longhua AU - Xiong, Jianqiu TI - Comparison of bacteremic pneumonia caused by <em>Escherichia coli</em> and <em>Klebsiella pneumoniae</em> AID - 10.15537/smj.2024.45.3.20230428 DP - 2024 Mar 01 TA - Saudi Medical Journal PG - 241--251 VI - 45 IP - 3 4099 - http://smj.org.sa/content/45/3/241.short 4100 - http://smj.org.sa/content/45/3/241.full SO - Saudi Med J2024 Mar 01; 45 AB - Objectives: To compare the prognosis of bacteremic pneumonia caused by Klebsiella pneumoniae (K. pneumoniae) and Escherichia coli (E. coli) pathogens.Methods: A retrospective analysis was carried out on the clinical data of 162 patients who were diagnosed with bacterial pneumonia caused by either K. pneumoniae or E. coli between 2016-2019. The primary outcome of the analysis was the patients’ 30-day mortality rate.Results: There were 82 patients in the E. coli bacteremic pneumonia (E. coli-BP) group and 80 patients in the K. pneumoniae bacteremic pneumonia (KP-BP) group. The 30-day mortality rate was 43.75% (n=35/80) in the KP-BP group and 21.95% (n=18/82) in the E. coli-BP group (p&lt;0.001). Following the adjustment for confounding variables in 4 distinct models, the hazard ratios for the primary outcome in KP-BP were determined to be 0.70 (95% confidence interval [CI]: [0.44-1.02]) in Model 1, 0.72 (95% CI: [0.46-1.14]) in Model 2, 0.99 (95% CI: [0.57-1.73]) in Model 3, and 1.22 (95% CI: [0.69-2.18]) in Model 4.Conclusion: Patients diagnosed with KP-BP exhibited a similar prognosis as those diagnosed with E. coli-BP. For patients with KP-BP, the risk of mortality was significantly higher for those who were in the intensive care unit, were infected with carbapenem-resistant strains, or had a high sequential organ failure assessment score. In patients with E. coli-BP, the Pitt bacteremia score was strongly associated with the 30-day mortality rate.