PT  - JOURNAL ARTICLE
AU  - Çelik, Mehmet
AU  - Arslan, Yusuf
AU  - Topcu, Ertuğrul
AU  - Serhat Şahinoğlu, Mustafa
AU  - Altındağ, Deniz
AU  - Gürbüz, Esra
AU  - Atalay, Ebru
AU  - Kışlak Demircan, Sümeyye
AU  - Emre, Salih
AU  - Kırık, Yasemin
AU  - Yürük Atasoy, Pınar
AU  - Özer, Deniz
AU  - İpek, Davut
AU  - Doğan, Ebru
AU  - Bilgiç Atlı, Seval
AU  - Gülderen Kuşçu, Evrim
AU  - Alkan, Sevil
AU  - Çiçek, Yeliz
AU  - Yüksekkaya, Esra
AU  - Aldemir, Özlem
AU  - Şahin, Ahmet
AU  - Yekta Ürkmez, Fatma
AU  - Özdemir Al, Sevda
AU  - Boran, Riyad
AU  - Oğuz Mızrakçı, Serpil
AU  - Kübra Dindar Demiray, Emine
AU  - Reşat Ceylan, Mehmet
AU  - Erdoğdu, Hamza
AU  - Tekin, Süda
TI  - Investigation of hematologic findings related to brucellosis in Anatolian region
AID  - 10.15537/smj.2024.45.5.20230847
DP  - 2024 May 01
TA  - Saudi Medical Journal
PG  - 495--501
VI  - 45
IP  - 5
4099  - http://smj.org.sa/content/45/5/495.short
4100  - http://smj.org.sa/content/45/5/495.full
SO  - Saudi Med J2024 May 01; 45
AB  - Objectives: To investigate the prevalence of hematologic findings and the relationship between hemogram parameters and brucellosis stages in patients.Methods: This multi-center study included patients older than 16 years of age who were followed up with a diagnosis of brucellosis. Patients’ results, including white blood cell, hemoglobin, neutrophil, lymphocyte, monocyte, mean platelet volume, platelet and eosinophil counts were analyzed at the initial diagnosis.Results: In this study 51.3% of the patients diagnosed with brucellosis were male. The age median was 45 years for female and 41 years for male. A total of 55.1% of the patients had acute brucellosis, 28.2% had subacute, 7.4% had chronic and 9% had relapse. The most common hematologic findings in brucellosis patients were anemia (25.9%), monocytosis (15.9%), eosinopenia (10.3%), and leukocytosis (7.1%). Pancytopenia occurred in 0.8% of patients and was more prominent in the acute phase. The acute brucellosis group had lower white blood cell, hemoglobin, neutrophil, eosinophil, and platelet counts and mean platelet volume, and higher monocyte counts compared to subacute and chronic subgroups.Conclusion: It was noteworthy that in addition to anemia and monocytosis, eosinopenia was third most prominent laboratory findings in the study. Pancytopenia and thrombocytopenia rates were low.