RT Journal Article
SR Electronic
T1 Investigation of hematologic findings related to brucellosis in Anatolian region
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 495
OP 501
DO 10.15537/smj.2024.45.5.20230847
VO 45
IS 5
A1 Çelik, Mehmet
A1 Arslan, Yusuf
A1 Topcu, Ertuğrul
A1 Serhat Şahinoğlu, Mustafa
A1 Altındağ, Deniz
A1 Gürbüz, Esra
A1 Atalay, Ebru
A1 Kışlak Demircan, Sümeyye
A1 Emre, Salih
A1 Kırık, Yasemin
A1 Yürük Atasoy, Pınar
A1 Özer, Deniz
A1 İpek, Davut
A1 Doğan, Ebru
A1 Bilgiç Atlı, Seval
A1 Gülderen Kuşçu, Evrim
A1 Alkan, Sevil
A1 Çiçek, Yeliz
A1 Yüksekkaya, Esra
A1 Aldemir, Özlem
A1 Şahin, Ahmet
A1 Yekta Ürkmez, Fatma
A1 Özdemir Al, Sevda
A1 Boran, Riyad
A1 Oğuz Mızrakçı, Serpil
A1 Kübra Dindar Demiray, Emine
A1 Reşat Ceylan, Mehmet
A1 Erdoğdu, Hamza
A1 Tekin, Süda
YR 2024
UL http://smj.org.sa/content/45/5/495.abstract
AB Objectives: To investigate the prevalence of hematologic findings and the relationship between hemogram parameters and brucellosis stages in patients.Methods: This multi-center study included patients older than 16 years of age who were followed up with a diagnosis of brucellosis. Patients’ results, including white blood cell, hemoglobin, neutrophil, lymphocyte, monocyte, mean platelet volume, platelet and eosinophil counts were analyzed at the initial diagnosis.Results: In this study 51.3% of the patients diagnosed with brucellosis were male. The age median was 45 years for female and 41 years for male. A total of 55.1% of the patients had acute brucellosis, 28.2% had subacute, 7.4% had chronic and 9% had relapse. The most common hematologic findings in brucellosis patients were anemia (25.9%), monocytosis (15.9%), eosinopenia (10.3%), and leukocytosis (7.1%). Pancytopenia occurred in 0.8% of patients and was more prominent in the acute phase. The acute brucellosis group had lower white blood cell, hemoglobin, neutrophil, eosinophil, and platelet counts and mean platelet volume, and higher monocyte counts compared to subacute and chronic subgroups.Conclusion: It was noteworthy that in addition to anemia and monocytosis, eosinopenia was third most prominent laboratory findings in the study. Pancytopenia and thrombocytopenia rates were low.