PT - JOURNAL ARTICLE AU - AlRahimi, Jamilah S. AU - Ismail, Yasser M. AU - Aljubairi, Noor A. AU - Kutob, Nawal W. AU - Bakulka, Ghadi S. AU - Ahmed, Ruqayyah A. AU - Ahmed, Fatima A. AU - Haneef, Ali A. TI - Assessing the correlation between the degree of tricuspid regurgitation and pulmonary hypertension AID - 10.15537/smj.2024.45.6.20240071 DP - 2024 Jun 01 TA - Saudi Medical Journal PG - 572--577 VI - 45 IP - 6 4099 - http://smj.org.sa/content/45/6/572.short 4100 - http://smj.org.sa/content/45/6/572.full SO - Saudi Med J2024 Jun 01; 45 AB - Objectives: To evaluate the relationship between severity of tricuspid regurgitation (TR) and pulmonary hypertension.Methods: Cross-sectional study of 118 patients with pulmonary hypertension was carried out at a single center in Jeddah, Saudi Arabia, between 2018-2021. Patients who had pulmonary or tricuspid valves organic diseases, previously undergone tricuspid or pulmonary valve surgeries, had permanent pacemakers or critically ill were excluded.Results: A high proportion of patients were women (n=100, 85%) and obese (n=57, 48%). Patients with more than mild TR had higher systolic pulmonary artery pressure (sPAP) than those with trivial or mild regurgitation (p<0.001). There was a significant association between severity of TR (p<0.001) and right chambers size (p=0.001). Furthermore, pulmonary artery pressure (PAP) was significantly higher in patients with mild right ventricular impairment (p=0.001).Conclusion: Increase in degree of TR and right atrial size were predictors of elevated sPAP. Our findings highlight the interplay among TR, right heart size, ventricular function, and PAP. Understanding these associations can aid in risk stratification, monitoring disease progression, and potentially guiding treatment in those patients.