PT  - JOURNAL ARTICLE
AU  - Samargandi, Ramy
AU  - Bernard, Mathilde
AU  - Miquelestorena-Standley, Elodie
AU  - Nail, Louis Romée Le
TI  - Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma
AID  - 10.15537/smj.2024.45.6.20230720
DP  - 2024 Jun 01
TA  - Saudi Medical Journal
PG  - 633--638
VI  - 45
IP  - 6
4099  - http://smj.org.sa/content/45/6/633.short
4100  - http://smj.org.sa/content/45/6/633.full
SO  - Saudi Med J2024 Jun 01; 45
AB  - Chondroblastoma is a rare benign cartilaginous tumor that accounts for approximately 1% of bone tumors, but it can be associated with lung metastasis in extremely rare cases, leading to a poor prognosis and death. Herein, we report the case of a 19-year-old male patient who presented with an aggressive chondroblastoma of the proximal humerus and bilateral lung metastasis. The patient was treated with wide local resection, partial metastasectomy, and denosumab. Denosumab treatment was effective in controlling metastatic progression and preventing local recurrence.