RT Journal Article SR Electronic T1 Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 633 OP 638 DO 10.15537/smj.2024.45.6.20230720 VO 45 IS 6 A1 Samargandi, Ramy A1 Bernard, Mathilde A1 Miquelestorena-Standley, Elodie A1 Nail, Louis Romée Le YR 2024 UL http://smj.org.sa/content/45/6/633.abstract AB Chondroblastoma is a rare benign cartilaginous tumor that accounts for approximately 1% of bone tumors, but it can be associated with lung metastasis in extremely rare cases, leading to a poor prognosis and death. Herein, we report the case of a 19-year-old male patient who presented with an aggressive chondroblastoma of the proximal humerus and bilateral lung metastasis. The patient was treated with wide local resection, partial metastasectomy, and denosumab. Denosumab treatment was effective in controlling metastatic progression and preventing local recurrence.