RT Journal Article SR Electronic T1 Evaluation of candidemia risk factors and Candida species distribution in intensive care units among patients with and without COVID-19 JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 606 OP 616 DO 10.15537/smj.2024.45.6.20240102 VO 45 IS 6 A1 Uyar, Cemile A1 Yıldız, Emel A1 Genç, Özlem A1 Ak, Öznur A1 Koçak, Emel A1 Alkan, Sevil A1 Balcı, Canan A1 Korkmaz, Pınar A1 Özatağ, Duru Mıstanoğlu A1 Aslan, Halil YR 2024 UL http://smj.org.sa/content/45/6/606.abstract AB Objectives: To assess the risk variables related to the types of candidemia for each patient, who was admitted into the intensive care unit regardless of the patient with or without complete diagnosis of COVID-19, during the period of March 2019 to December 2022.Methods: The evaluation comparison of demographic and clinical data of COVID-19 positive and negative patients with candidemia confirmed in blood, 113 cases were assessed. Variables such as gender, age, age of hospitalization, history of hospitalization, concurrently infection, The acute physiology and chronic health evaluation-II scores, comorbidity checking, intubation, central venous catheter use, parenteral nutrition use, steroid use, antibiotic use, lymphopenia, and laboratory variables were evaluated. Candida species distribution, antifungal susceptibility in blood culture were determined.Results: Coronavirus disease-19 was present in 62.8% of cases confirmed candidemia, and these cases were significantly different from COVID-19 negative cases. Significance was found in more intubation, central venous catheter use, parenteral nutrition, and steroid therapy in Group 2. There was no significance with species distribution and associated infection. In total, COVID-19 positive had higher hemoglobin, aspartate aminotransferase, alanine transaminase, and white blood cell levels, which may be associated with the possibility of revealing and controlling candidemia.Conclusion: Candida albicans and Candida Parapsilosis (C. parapsilosis) are the species seen in infected COVID-19 patients, while C. parapsilosis and Candida tropicalis are found in non-COVID-19 ones. Risk factors were intubation, parenteral nutrition, central venous catheter, and steroid in the COVID-19 group.