PT  - JOURNAL ARTICLE
AU  - Al Saud, Aljoharah A.
AU  - AlRomaizan, Muneerah R.
AU  - Alkhunizan, Muath A.
TI  - Thrombocytopenia following iron repletion with ferrous gluconate
AID  - 10.15537/smj.2024.45.8.20231003
DP  - 2024 Aug 01
TA  - Saudi Medical Journal
PG  - 848--850
VI  - 45
IP  - 8
4099  - http://smj.org.sa/content/45/8/848.short
4100  - http://smj.org.sa/content/45/8/848.full
SO  - Saudi Med J2024 Aug 01; 45
AB  - Immune thrombocytopenia (ITP) is an autoimmune disorder marked by low platelet counts that puts patients at risk for spontaneous bleeding. A rare trigger for ITP is iron repletion, which has only been reported in a few cases. In this article, we present a unique case of a 54-year-old male with a history of recurrent ITP who experienced rapid thrombocytopenia following iron repletion with ferrous gluconate. Discontinuation of ferrous medications resulted in platelet counts returning to the normal baseline. Following more than 30 years of the patient’s clinical timeline, this case demonstrates the chronic nature of ITP and the complexity of its causes. Further studies are needed to determine the prevalence of iron repletion-induced thrombocytopenia and its underlying mechanisms.