PT - JOURNAL ARTICLE AU - Xie, Ling AU - Chen, Yun TI - The protagonist of contemporary and emerging nanotechnology-based theranostics and therapeutic approaches in reshaping intensive care unit AID - 10.15537/smj.2024.45.8.20240069 DP - 2024 Aug 01 TA - Saudi Medical Journal PG - 759--770 VI - 45 IP - 8 4099 - http://smj.org.sa/content/45/8/759.short 4100 - http://smj.org.sa/content/45/8/759.full SO - Saudi Med J2024 Aug 01; 45 AB - To maintain a clean and hygienic environment in the intensive care unit (ICU) is crucial for ensuring patient safety, preventing infections, and reducing healthcare-associated complications. With the increasing prevalence of infections and the emergence of viral and bacterial resistance to standard antiseptics, there is a pressing need for innovative antiseptic solutions. Nanotechnology is increasingly being employed in medicine, particularly focusing on mitigating the activities of various pathogens, including those associated with hospital-acquired infections. This paper explores the current impact of nanotechnology, with a particular focus on bacterial infections and SARS-CoV-2, which significantly strain healthcare systems, and then discusses how nanotechnology can enhance existing treatment methodologies. We highlight the effectiveness of the nanotechnology-based bactericide Bio-Kil in reducing bacterial counts in an ICU. The aim is to educate healthcare professionals on the existing role and prospects of nanotechnology in addressing prevalent infectious diseases.