PT - JOURNAL ARTICLE AU - Mawkili, Wedad A. TI - The future of personalized medicine in Saudi Arabia AID - 10.15537/smj.2025.46.1.20240700 DP - 2025 Jan 01 TA - Saudi Medical Journal PG - 19--25 VI - 46 IP - 1 4099 - http://smj.org.sa/content/46/1/19.short 4100 - http://smj.org.sa/content/46/1/19.full SO - Saudi Med J2025 Jan 01; 46 AB - Personalized medicine is a healthcare approach that designs treatment plans of each patient, considering genetic, environmental, and lifestyle factors. This model leverages genomic information, advanced diagnostics, and data analytics to predict disease risk, optimize prevention strategies, and provide customized treatments. In Saudi Arabia, personalized medicine is gaining momentum, driven by the country’s Vision 2030 initiative, which aims to transform the healthcare sector by integrating advanced medical technologies and improving healthcare delivery. The Kingdom has made significant strides in genomics and bioinformatics, with initiatives such as the Saudi Human Genome Program and advancements in institutions i.e., King Faisal Specialist Hospital and Research Centre. Continued investment in research, education, and technology, alongside international collaborations, will be crucial in overcoming these challenges and realizing the full potential of personalized medicine. This review explores the current state, challenges, and future prospects of personalized medicine in Saudi Arabia, highlighting its transformative impact on healthcare delivery and patient outcomes.