PT  - JOURNAL ARTICLE
AU  - Budak, Gokcen Gurkok
AU  - Vatan, Aslı
AU  - Güçlü, Ertuğrul
AU  - Karabay, Oğuz
TI  - Concordance between homeostatic model assessment and triglyceride glucose index in assessing insulin resistance among HIV-infected patients
AID  - 10.15537/smj.2025.46.2.20240769
DP  - 2025 Feb 01
TA  - Saudi Medical Journal
PG  - 157--162
VI  - 46
IP  - 2
4099  - http://smj.org.sa/content/46/2/157.short
4100  - http://smj.org.sa/content/46/2/157.full
SO  - Saudi Med J2025 Feb 01; 46
AB  - Objectives: To evaluate the concordance between the triglyceride glucose (TyG) index and the homeostatic model assessment of insulin resistance (HOMA-IR) in assessing insulin resistance (IR) in people living with HIV (PLWH). Additionally, we aimed to estimate a cut-off value for the TyG index in PLWH.Methods: This retrospective, observational study included medical records of patients diagnosed with HIV at Sakarya Training and Research Hospital from January 2019 to January 2024. Based on their HOMA-IR levels, PLWH patients were divided into 2 groups: Group A (patients without IR) and Group B (patients with IR).Results: In this study, insulin resistance was investigated in 147 people living with HIV (PLWH) between the ages of 18-68. Our results showed a significant positive linear relationship between HOMA-IR and the TyG index (r=0.628, p<0.001). We found the TyG Index cut-off value to predict IR in people living with HIV (PLWH) to be 8.25.Conclusion: Our study identified correlation between the TyG index and HOMA IR index in PLWH. The TyG index may serve as an effective alternative to HOMA-IR for evaluating insulin resistance in PLWH.”.