PT - JOURNAL ARTICLE AU - AlAttas, Safia A. AU - Zahran, Fat’heya M. AU - Turkistany, Shereen A. TI - <em>Nigella sativa</em> and its active constituent thymoquinone in oral health AID - 10.15537/smj.2016.3.13006 DP - 2016 Mar 01 TA - Saudi Medical Journal PG - 235--244 VI - 37 IP - 3 4099 - http://smj.org.sa/content/37/3/235.short 4100 - http://smj.org.sa/content/37/3/235.full SO - Saudi Med J2016 Mar 01; 37 AB - In this review, we summarized published reports that investigated the role of Nigella sativa (NS) and its active constituent, thymoquinone (TQ) in oral health and disease management. The literature studies were preliminary and scanty, but the results revealed that black seed plants have a potential therapeutic effect for oral and dental diseases. Such results are encouraging for the incorporation of these plants in dental therapeutics and hygiene products. However, further detailed preclinical and clinical studies at the cellular and molecular levels are required to investigate the mechanisms of action of NS and its constituents, particularly TQ.