RT Journal Article SR Electronic T1 Nigella sativa and its active constituent thymoquinone in oral health JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 235 OP 244 DO 10.15537/smj.2016.3.13006 VO 37 IS 3 A1 AlAttas, Safia A. A1 Zahran, Fat’heya M. A1 Turkistany, Shereen A. YR 2016 UL http://smj.org.sa/content/37/3/235.abstract AB In this review, we summarized published reports that investigated the role of Nigella sativa (NS) and its active constituent, thymoquinone (TQ) in oral health and disease management. The literature studies were preliminary and scanty, but the results revealed that black seed plants have a potential therapeutic effect for oral and dental diseases. Such results are encouraging for the incorporation of these plants in dental therapeutics and hygiene products. However, further detailed preclinical and clinical studies at the cellular and molecular levels are required to investigate the mechanisms of action of NS and its constituents, particularly TQ.