PT  - JOURNAL ARTICLE
AU  - Alyami, Abdulaziz M.
AU  - Kaabia, Naoufel M.
AU  - AlQasim, Marzouq A.
AU  - Doghaim, Fahad S. Al
AU  - Albehlal, Lulu B.
AU  - Ahmed, Medina A.
AU  - Aidaroos, Amal Y. Al
AU  - Odayani, Abdurahman Al
TI  - <em>Chryseobacterium</em>/<em>Elizabethkingia species</em> infections in Saudi Arabia
AID  - 10.15537/smj.2020.3.24985
DP  - 2020 Mar 01
TA  - Saudi Medical Journal
PG  - 309--313
VI  - 41
IP  - 3
4099  - http://smj.org.sa/content/41/3/309.short
4100  - http://smj.org.sa/content/41/3/309.full
SO  - Saudi Med J2020 Mar 01; 41
AB  - Objectives: To describe the epidemiological, clinical, and outcome data of patients infected or colonized with Chryseobacterium/Elizabethkingia spp including antibiotic susceptibility patterns.Methods: This retrospective study was conducted at Prince Sultan Military Medical City, Riyadh, Saudi Arabia. All patients infected or colonized by Chryseobacterium /Elizabethkingia spp who were admitted between June 2013 and May 2019 were included. Data were extracted from patient electronic medical records.Results: We enrolled 27 patients (13 males and 14 females) with a mean age of 35.6 years. Chryseobacterium/Elizabethkingia spp were isolated from blood cultures (n=13, 48%) and tracheal aspirations (n=11, 41%). The most frequent species isolated was Elizabethkingia meningoseptica (n=22). Although 6 patients were considered colonized, the remaining 21 patients presented with ventilator associated pneumonia (n=9), central line associated bloodstream infection (n=4), septic shock (n=4), or isolated bacteremia (n=4). In 25 cases the infections were health-care related. Three patients (11%) died within 28 days. Twenty-six isolates (96.5%) were resistant to carbapenems. Moxifloxacin and cotrimoxazole were the most active antibiotics.Conclusion: Chryseobacterium/Elizabethkingia spp infection is rare, but can be responsible for severe hospital acquired infections. Cotrimoxazole and fluoroquinolone are the most effective antibiotic treatments.