RT Journal Article SR Electronic T1 Diagnostic approaches to and management options for patulous eustachian tube JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 572 OP 582 DO 10.15537/smj.2020.6.25083 VO 41 IS 6 A1 Tawfiq Khurayzi A1 Saad Alenzi A1 Anwar Alshehri A1 Abdurrahman Alsanosi YR 2020 UL http://smj.org.sa/content/41/6/572.abstract AB Objectives: To systematically review the literature and to summarize all evidence related to the diagnosis and management of patulous eustachian tube.Methods: The present study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.Results: Overall, 59 articles were retrieved and included in the analysis. Studies investigating treatments enrolled 1279 patients collectively, with follow-up duration varying from few days and up to 2 years. Eight studies reported medical treatments with intranasal saline instillation as the most frequently studied option. Other studies reported various surgical treatments varying from simple tympanostomy to invasive procedures targeting the orifice of the ET or the anatomical features surrounding it. In addition, 10 studies including 367 subjects investigated different diagnostic methods.Conclusion: Currently, there is a wide spectrum of diagnostic and therapeutic interventions with minimal clinical efficacy, a persistent lack of systematic guidelines, and several gaps in previous research endeavours.PROSPERO REG. NO. CRD: 1644000