PT - JOURNAL ARTICLE AU - Alahmadi, Asma A. AU - Bawazir, Osama A. AU - Rajab, Mohannad K. AU - Althobaiti, Ibtihal A. AU - Bawazir, Abdullah O. AU - Abi Sheffah, Firas R. AU - Al-Tammas, Anas H. AU - Marglani, Osama A. AU - Heaphy, John C. AU - Alherabi, Ameen Z. TI - Thyroglossal duct surgery. <em>What is the acceptable recurrence rate?</em> AID - 10.15537/smj.2020.8.25169 DP - 2020 Aug 01 TA - Saudi Medical Journal PG - 878--882 VI - 41 IP - 8 4099 - http://smj.org.sa/content/41/8/878.short 4100 - http://smj.org.sa/content/41/8/878.full SO - Saudi Med J2020 Aug 01; 41 AB - Objectives: To present experiences of different specialties in the treatment of thyroglossal duct cysts (TGDCs) and subsequent complications in multiple centers.Methods: A retrospective cross-sectional study of all cases of TGDC for a period of 11 years from 2008-2019 by different departments from 3 different centers in Jeddah, Kingdom of Saudi Arabia (King Faisal Specialist Hospital &amp; Research Centre, Bakhsh Hospital and International Medical Center).Results: Forty-nine patients were included. The type of surgery performed plays a significant role in recurrence (p&lt;0.001). The Sistrunk procedure had a lower recurrence rate (0%) than simple excision (70%) and has showed a significantly long recurrence-free interval (p&lt;0.001). Higher recurrence rates are associated with higher postoperative complications (p=0.002). Patients who underwent pre-operative fine needle aspiration did not have any recurrence during the follow-up period.Conclusion: The Sistrunk procedure is the gold standard technique with the highest recurrence-free interval rate. Fine needle aspiration could be recommended as a less invasive procedure to exclude malignancy.