PT  - JOURNAL ARTICLE
AU  - Sobaih, Badr H.
TI  - Long-term cognitive outcome of very low birth-weight Saudi preterm infants at the corrected age of 24-36 month
AID  - 10.15537/smj.2018.4.21989
DP  - 2018 Apr 01
TA  - Saudi Medical Journal
PG  - 368--372
VI  - 39
IP  - 4
4099  - http://smj.org.sa/content/39/4/368.short
4100  - http://smj.org.sa/content/39/4/368.full
SO  - Saudi Med J2018 Apr 01; 39
AB  - Objectives: To assess infants’ cognitive function at the corrected age of 24-36 months, and to identify factors associated with adverse outcome and examine the correlation between Bayley Infants Neurodevelopmental Screener (BINS) score and Gesell Schedule of Child Development (GSCD).Methods: This retrospective study was performed on Saudi very low birth-weight (VLBW) infants born in King Khalid University Hospital, Riyadh, Saudi Arabia between 1997 and 2014 by the use of BINS as screening test and GSCD as definitive test.Results: Of 561 enrolled infants, 367 (65.4%) continued to follow-up. Three-hundred and fifteen infants (85.6%) had a normal cognitive function. In addition to lower birth weight (beta = -0.003) (p<0.001), male gender (OR =3.9) (p=0.001)and cerebral palsy (OR =33.9) (p<0.001) were the strongest factors associated with poor cognitive outcome. Approximately 75.4% of infants with normal BINS score had normal cognitive function and 7.6% of total infants had sever cognitive impairment.Conclusion: The majority of VLBW infants in our center have normal cognitive function at the corrected age of 24-36 months. Male gender, lower birth weight, and cerebral palsy are major predictors of poor outcome. The BINS scores were correlated with GSCD as a valid predictor for future developmental outcome.