RT Journal Article SR Electronic T1 Primary mucinous adenocarcinoma of the eyelid JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 940 OP 945 DO 10.15537/smj.2018.9.22512 VO 39 IS 9 A1 Albasri, Abdulkader M. A1 Ansari, Irfan A. A1 Aljohani, Abdulaziz R. A1 Alhujaily, Ahmed S. YR 2018 UL http://smj.org.sa/content/39/9/940.abstract AB Primary mucinous adenocarcinoma (PMA) of the eyelid is an exceptionally rare clinical entity. Often, it mimics with benign lesions on clinical examination and with metastatic mucinous adenocarcinoma on histological examinations. We report a case of PMA in a 60-year-old male patient who came with a slow-growing, painless swelling near the lower lid of the left eye. Excisional biopsy from the mass revealed a mucinous adenocarcinoma. To differentiate it from a metastatic mucinous adenocarcinoma, a wide range of immunohistochemistry panel was run. The tumor cells showed strong positivity for cytokeratin7, cytokeratin5/6, p63, estrogen receptor, progesterone receptor and negativity for cytokeratin20. Moreover, extensive metastatic work-up did not show any primary malignancy elsewhere, hence a final diagnosis of PMA was made. We report a rare case of PMA from the Madinah region of Saudi Arabia.