PT  - JOURNAL ARTICLE
AU  - Wang, Qi
AU  - Liu, Han
AU  - Sun, Siqiao
AU  - Cheng, Zhihua
AU  - Zhang, Yang
AU  - Sun, Xiwei
AU  - Wang, Zhongying
AU  - Wang, Shuai
TI  - Neutrophil-to-lymphocyte ratio is effective prognostic indicator for post-amputation patients with critical limb ischemia
AID  - 10.15537/smj.2017.1.15936
DP  - 2017 Jan 01
TA  - Saudi Medical Journal
PG  - 24--29
VI  - 38
IP  - 1
4099  - http://smj.org.sa/content/38/1/24.short
4100  - http://smj.org.sa/content/38/1/24.full
SO  - Saudi Med J2017 Jan 01; 38
AB  - Objectives: To confirm whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are indicators for the prognosis of post-amputation patients with critical limb ischemia (CLI).Methods: In this retrospective observational study a total 270 post-amputation patients with CLI were included between January 2010 and December 2014 in the First Hospital of Jilin University, Changchun, China. The neutrophil and lymphocyte counts were recorded before amputations. Neutrophil-to-lymphocyte ratio was calculated and NLR ≥8.08 was defined as elevated. Logistic regression analysis was conducted to test the prognostic value.Results: According to the statistical analysis, it was indicated that NLR ≥8.08 (odds ratio [OR] 26.228, 95% confidence interval [CI]: 5.801-118.583, p<0.001), PLR ≥237.14 (OR: 3.464, 95% CI: 1.289-9.308, p=0.014) and coronary heart disease (OR: 2.739, 95% CI: 1.060-7.082, p=0.038) were the independent prognostic indicators for the patients.Conclusion: Neutrophil-to-lymphocyte ratio, PLR, and coronary heart disease are independent prognostic indicators for post-amputation patients with CLI.