RT Journal Article
SR Electronic
T1 Neutrophil-to-lymphocyte ratio is effective prognostic indicator for post-amputation patients with critical limb ischemia
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 24
OP 29
DO 10.15537/smj.2017.1.15936
VO 38
IS 1
A1 Wang, Qi
A1 Liu, Han
A1 Sun, Siqiao
A1 Cheng, Zhihua
A1 Zhang, Yang
A1 Sun, Xiwei
A1 Wang, Zhongying
A1 Wang, Shuai
YR 2017
UL http://smj.org.sa/content/38/1/24.abstract
AB Objectives: To confirm whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are indicators for the prognosis of post-amputation patients with critical limb ischemia (CLI).Methods: In this retrospective observational study a total 270 post-amputation patients with CLI were included between January 2010 and December 2014 in the First Hospital of Jilin University, Changchun, China. The neutrophil and lymphocyte counts were recorded before amputations. Neutrophil-to-lymphocyte ratio was calculated and NLR ≥8.08 was defined as elevated. Logistic regression analysis was conducted to test the prognostic value.Results: According to the statistical analysis, it was indicated that NLR ≥8.08 (odds ratio [OR] 26.228, 95% confidence interval [CI]: 5.801-118.583, p<0.001), PLR ≥237.14 (OR: 3.464, 95% CI: 1.289-9.308, p=0.014) and coronary heart disease (OR: 2.739, 95% CI: 1.060-7.082, p=0.038) were the independent prognostic indicators for the patients.Conclusion: Neutrophil-to-lymphocyte ratio, PLR, and coronary heart disease are independent prognostic indicators for post-amputation patients with CLI.