RT Journal Article SR Electronic T1 Hormone receptor status and survival of medullary breast cancer patients JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 156 OP 162 DO 10.15537/smj.2017.2.18055 VO 38 IS 2 A1 Asude Aksoy A1 Hatice Odabas A1 Serap Kaya A1 Oktay Bozkurt A1 Mustafa Degirmenci A1 Turkan O. Topcu A1 Aydın Aytekin A1 Erkan Arpaci A1 Nilufer Avci A1 Kezban N. Pilanci A1 Havva Y. Cinkir A1 Yakup Bozkaya A1 Yalcin Cirak A1 Mahmut Gumus YR 2017 UL http://smj.org.sa/content/38/2/156.abstract AB Objectives: To analyze the relationship between clinical features, hormonal receptor status, and survival in patients who were diagnosed with medullary breast cancer (MBC).Methods: Demographic characteristics, histopathological features, and survival statuses of 201 patients diagnosed with MBC between 1995 and 2015 were retrospectively recorded. Survival analyses were conducted with uni- and multivariate cox regression analysis.Results: Median follow-up time was 54 (4-272) months. Median patient age at the time of diagnosis was 47 years old (26-90). Of the patients, 91.5% were triple negative. Five-year recurrence free survival time (RFS) rate was 87.4% and overalll survival (OS) rate 95.7%. For RFS, progesterone receptor (PR) negativity, atypical histopathological evaluation, absence of lymphovascular invasion, smaller tumor, lower nodal involvement were found to be favourable prognostic factors by univariate analysis (p<0.05). The PR negativity and smaller tumor were found to be favourable factors by univariate analysis (p<0.05). However, none of these factors were determined as significant independent prognostic factors for OS (p>0.05).Conclusion: Turkish MBC patients exhibited good prognosis, which was comparable with survival outcomes achieved in the literature. The PR negativity was related to a better RFS and OS rates.