RT Journal Article
SR Electronic
T1 Assessment of Crohn’s disease activity by Doppler sonography
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 391
OP 395
DO 10.15537/smj.2017.4.17855
VO 38
IS 4
A1 Ying Na
A1 Jian Zhou
A1 Xiang-Min Xiao
A1 Wen-Xing Zhang
A1 Hong-Lei Gao
A1 Yang Wang
A1 Xiao-Yan Han
A1 Zuo-Cheng Sun
A1 Hui-Min Xu
YR 2017
UL http://smj.org.sa/content/38/4/391.abstract
AB Objectives: To investigate the diagnostic accuracy of ultrasound for evaluation of inflammatory activity in patients with Crohn’s disease (CD).Methods: Fifty-six patients with histologically proven CD (39 with active, 17 with inactive disease) and 30 healthy volunteers as a control group were enrolled in the study at WeiFang People’s Hospital, Weifang Province, China from October 2012 to December 2014. Bowel wall thickness, and vascularity pattern were measured by Doppler ultrasound.Results: There was a significant difference in flow volume of the superior mesenteric artery (585 ± 235 ml/min) in the patients with active disease, compared with those with inactive disease (401 ± 238 ml/min) and the control group (390 ± 189 ml/min, p<0.001). Wall thickness was 5.1 ± 1.5 mm in the active CD group, 3.3 ± 1.6 mm in the inactive disease group (p<0.001) and <3 mm in the control group. Resistance index in the thickened bowel wall showed some differences: 0.68 ± 0.05 in the active disease group, 0.78 ± 0.08 in the inactive disease group, and 0.85 ± 0.07 in the control group (p<0.05).Conclusion: Doppler ultrasound is a useful diagnostic tool in detecting CD and assessing inflammatory activity.