PT  - JOURNAL ARTICLE
AU  - Amin, Zulkifli
AU  - Rahmawati, Fitriana N.
TI  - Recent insight into potential acute respiratory distress syndrome
AID  - 10.15537/smj.2017.4.15843
DP  - 2017 Apr 01
TA  - Saudi Medical Journal
PG  - 344--349
VI  - 38
IP  - 4
4099  - http://smj.org.sa/content/38/4/344.short
4100  - http://smj.org.sa/content/38/4/344.full
SO  - Saudi Med J2017 Apr 01; 38
AB  - Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury, characterized by increased pulmonary capillary endothelial cells and alveolar epithelial cells permeability leading to respiratory failure in the absence of cardiac failure. Despite recent advances in treatments, the overall mortality because of ARDS remains high. Biomarkers may help to diagnose, predict the severity, development, and outcome of ARDS in order to improve patient care and decrease morbidity and mortality. This review will focus on soluble receptor for advanced glycation end-products, soluble tumor necrosis factor-receptor 1, Interluken-6 (IL-6), IL-8, and plasminogen activator inhibitor-1, which have a greater potential based on recent studies.