RT Journal Article
SR Electronic
T1 Recent insight into potential acute respiratory distress syndrome
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 344
OP 349
DO 10.15537/smj.2017.4.15843
VO 38
IS 4
A1 Zulkifli Amin
A1 Fitriana N. Rahmawati
YR 2017
UL http://smj.org.sa/content/38/4/344.abstract
AB Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury, characterized by increased pulmonary capillary endothelial cells and alveolar epithelial cells permeability leading to respiratory failure in the absence of cardiac failure. Despite recent advances in treatments, the overall mortality because of ARDS remains high. Biomarkers may help to diagnose, predict the severity, development, and outcome of ARDS in order to improve patient care and decrease morbidity and mortality. This review will focus on soluble receptor for advanced glycation end-products, soluble tumor necrosis factor-receptor 1, Interluken-6 (IL-6), IL-8, and plasminogen activator inhibitor-1, which have a greater potential based on recent studies.