RT Journal Article
SR Electronic
T1 Dengue fever
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1025
OP 1033
DO 10.15537/smj.2017.10.20965
VO 38
IS 10
A1 Badreddine, Samar
A1 Al-Dhaheri, Fahmi
A1 Al-Dabbagh, Ammar
A1 Al-Amoudi, Abdulrahman
A1 Al-Ammari, Maged
A1 Elatassi, Nader
A1 Abbas, Haytham
A1 Magliah, Rami
A1 Malibari, Abdulbasit
A1 Almoallim, Hani
YR 2017
UL http://smj.org.sa/content/38/10/1025.abstract
AB Objectives: To delineate the clinical features and outcomes of dengue infection and to guide clinician of early diagnosis and identification of risks factors for dengue hemorrhagic fever.Methods: This study is a retrospective cross-sectional. Clinical records of 567 patients with a confirmed diagnosis of dengue infection, admitted to a single hospital in Jeddah, Saudi Arabia, between January 2010 and June 2014 were reviewed.Results: Dengue infection was most common in adult males. Sixty-eight percent of infections were in Saudi nationals. In addition to the diagnostic clinical features, leucopenia and thrombocytopenia were typical of dengue infection. Approximately 4.1% of adult patients and 7.1% of pediatric patients developed dengue hemorrhagic fever (DHF). Abdominal pain and vomiting were more common in patients developing DHF. Mean platelet count was lower in adult, but not pediatric patients developing DHF. Peak alanine aminotransferase (ALT) was higher in adult and pediatric patients developing DHF. Three patients died, 2 of them developed DHF. Ninety-eight percent of adult patients and 92% of pediatric patients made a full recovery.Conclusions: Dengue infection is common in Jeddah. Abdominal pain and vomiting, thrombocytopenia, and elevated ALT are typical of severe infection, which is more likely to be associated with significant morbidity and mortality.