RT Journal Article SR Electronic T1 Dengue fever JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1025 OP 1033 DO 10.15537/smj.2017.10.20965 VO 38 IS 10 A1 Badreddine, Samar A1 Al-Dhaheri, Fahmi A1 Al-Dabbagh, Ammar A1 Al-Amoudi, Abdulrahman A1 Al-Ammari, Maged A1 Elatassi, Nader A1 Abbas, Haytham A1 Magliah, Rami A1 Malibari, Abdulbasit A1 Almoallim, Hani YR 2017 UL http://smj.org.sa/content/38/10/1025.abstract AB Objectives: To delineate the clinical features and outcomes of dengue infection and to guide clinician of early diagnosis and identification of risks factors for dengue hemorrhagic fever.Methods: This study is a retrospective cross-sectional. Clinical records of 567 patients with a confirmed diagnosis of dengue infection, admitted to a single hospital in Jeddah, Saudi Arabia, between January 2010 and June 2014 were reviewed.Results: Dengue infection was most common in adult males. Sixty-eight percent of infections were in Saudi nationals. In addition to the diagnostic clinical features, leucopenia and thrombocytopenia were typical of dengue infection. Approximately 4.1% of adult patients and 7.1% of pediatric patients developed dengue hemorrhagic fever (DHF). Abdominal pain and vomiting were more common in patients developing DHF. Mean platelet count was lower in adult, but not pediatric patients developing DHF. Peak alanine aminotransferase (ALT) was higher in adult and pediatric patients developing DHF. Three patients died, 2 of them developed DHF. Ninety-eight percent of adult patients and 92% of pediatric patients made a full recovery.Conclusions: Dengue infection is common in Jeddah. Abdominal pain and vomiting, thrombocytopenia, and elevated ALT are typical of severe infection, which is more likely to be associated with significant morbidity and mortality.