TY - JOUR T1 - Dengue fever JF - Saudi Medical Journal JO - Saudi Med J SP - 1025 LP - 1033 DO - 10.15537/smj.2017.10.20965 VL - 38 IS - 10 AU - Samar Badreddine AU - Fahmi Al-Dhaheri AU - Ammar Al-Dabbagh AU - Abdulrahman Al-Amoudi AU - Maged Al-Ammari AU - Nader Elatassi AU - Haytham Abbas AU - Rami Magliah AU - Abdulbasit Malibari AU - Hani Almoallim Y1 - 2017/10/01 UR - http://smj.org.sa/content/38/10/1025.abstract N2 - Objectives: To delineate the clinical features and outcomes of dengue infection and to guide clinician of early diagnosis and identification of risks factors for dengue hemorrhagic fever.Methods: This study is a retrospective cross-sectional. Clinical records of 567 patients with a confirmed diagnosis of dengue infection, admitted to a single hospital in Jeddah, Saudi Arabia, between January 2010 and June 2014 were reviewed.Results: Dengue infection was most common in adult males. Sixty-eight percent of infections were in Saudi nationals. In addition to the diagnostic clinical features, leucopenia and thrombocytopenia were typical of dengue infection. Approximately 4.1% of adult patients and 7.1% of pediatric patients developed dengue hemorrhagic fever (DHF). Abdominal pain and vomiting were more common in patients developing DHF. Mean platelet count was lower in adult, but not pediatric patients developing DHF. Peak alanine aminotransferase (ALT) was higher in adult and pediatric patients developing DHF. Three patients died, 2 of them developed DHF. Ninety-eight percent of adult patients and 92% of pediatric patients made a full recovery.Conclusions: Dengue infection is common in Jeddah. Abdominal pain and vomiting, thrombocytopenia, and elevated ALT are typical of severe infection, which is more likely to be associated with significant morbidity and mortality. ER -