@article {Mismar994, author = {Ayman A. Mismar and Mohammad I. Mahseeri and Mutasim A. Al-Ghazawi and Firas W. Obeidat and Mai N. Albsoul and Mohammad S. Al-Qudah and Nader M. Albsoul}, title = {Wound infiltration with bupivacaine 0.5\% with or without adrenaline does not decrease pain after thyroidectomy}, volume = {38}, number = {10}, pages = {994--999}, year = {2017}, doi = {10.15537/smj.2017.10.20294}, publisher = {Saudi Medical Journal}, abstract = {Objectives: To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS).Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5\% was administered; Group B, bupivacaine 0.5\% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out.Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations.Conclusion: Local wound infiltration with bupivacaine 0.5\% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect.}, issn = {0379-5284}, URL = {https://smj.org.sa/content/38/10/994}, eprint = {https://smj.org.sa/content/38/10/994.full.pdf}, journal = {Saudi Medical Journal} }