RT Journal Article SR Electronic T1 Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 994 OP 999 DO 10.15537/smj.2017.10.20294 VO 38 IS 10 A1 Mismar, Ayman A. A1 Mahseeri, Mohammad I. A1 Al-Ghazawi, Mutasim A. A1 Obeidat, Firas W. A1 Albsoul, Mai N. A1 Al-Qudah, Mohammad S. A1 Albsoul, Nader M. YR 2017 UL http://smj.org.sa/content/38/10/994.abstract AB Objectives: To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS).Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out.Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations.Conclusion: Local wound infiltration with bupivacaine 0.5% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect.