TY - JOUR T1 - Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy JF - Saudi Medical Journal JO - Saudi Med J SP - 994 LP - 999 DO - 10.15537/smj.2017.10.20294 VL - 38 IS - 10 AU - Ayman A. Mismar AU - Mohammad I. Mahseeri AU - Mutasim A. Al-Ghazawi AU - Firas W. Obeidat AU - Mai N. Albsoul AU - Mohammad S. Al-Qudah AU - Nader M. Albsoul Y1 - 2017/10/01 UR - http://smj.org.sa/content/38/10/994.abstract N2 - Objectives: To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS).Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was measured using VAS at 2, 4, 6, 12, and 24 hours after surgery. A comparison between the 3 groups was carried out.Results: No significant differences among the 3 groups were observed at all time points (p=0.246). Visual analog scores were significantly lower at 12 and 24 hours after operations.Conclusion: Local wound infiltration with bupivacaine 0.5% does not decrease pain perception after thyroidectomy performed under general anesthesia, and adding adrenaline does not enhance its effect. ER -