RT Journal Article
SR Electronic
T1 A novel diagnosis scoring model to predict invasive pulmonary aspergillosis in the intensive care unit
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 140
OP 146
DO 10.15537/smj.2019.2.22940
VO 40
IS 2
A1 Rozaliyani, Anna
A1 Sedono, Rudyanto
A1 Jusuf, Anwar
A1 Rumende, Cleopas M.
A1 Aniwidyaningsih, Wahju
A1 Burhan, Erlina
A1 Prasenohadi
A1 Handayani, Diah
A1 Yunihastuti, Evy
A1 Siagian, Forman E.
A1 Jayusman, Achmad M.
A1 Rusli, Adria
A1 Sungkar, Saleha
A1 Prihartono, Joedo
A1 Hagen, Ferry
A1 Meis, Jacques F.
A1 Wahyuningsih, Retno
YR 2019
UL http://smj.org.sa/content/40/2/140.abstract
AB Objectives: To improve the quality of invasive pulmonary aspergillosis (IPA) management for intensive care unit (ICU) patients using a practical diagnostic scoring model.Methods: This nested case-control study aimed to determine the incidence of IPA in 405 ICU patients, between July 2012 and June 2014, at 6 hospitals in Jakarta, Indonesia. Phenotypic identifications and galactomannan (GM) tests of sera and lung excreta were performed in mycology laboratory, Parasitology Department, Faculty of Medicine, Universitas Indonesia in Jakarta, Indonesia.Results: The incidence of IPA in the ICUs was 7.7% (31 of 405 patients). A scoring model used for IPA diagnosis showed 4 variables as the most potential risk factors: lung excreta GM index (score 2), solid organ malignancy (score 2), pulmonary tuberculosis (score 2), and systemic corticosteroids (score 1). Patients were included in a high-risk group if their score was >2, and in a low-risk group if their score was <2.Conclusion: This study provides a novel diagnosis scoring model to predict IPA in ICU patients. Using this model, a more rapid diagnosis and treatment of IPA may be possible. The application of the diagnosis scoring should be preceded by specified pre-requisites.