PT  - JOURNAL ARTICLE
AU  - Kostić, Mirjana
AU  - Bedeković, Vladimir
AU  - Bastijančić-Kokić, Biserka
AU  - Lauc, Tomislav
TI  - Unnecessary prescribing of antibiotics to healthy/asymptomatic school-age carriers of potentially pathogenic bacteria
AID  - 10.15537/smj.2019.4.24004
DP  - 2019 Apr 01
TA  - Saudi Medical Journal
PG  - 405--408
VI  - 40
IP  - 4
4099  - http://smj.org.sa/content/40/4/405.short
4100  - http://smj.org.sa/content/40/4/405.full
SO  - Saudi Med J2019 Apr 01; 40
AB  - Objectives: To re-draw attention to the unnecessary prescribing of antibiotics.Methods: We monitored nasopharyngeal colonization by 3 potentially pathogenic bacteria, Streptococcus pyogenes, Streptococcus pneumoniae, and Haemophilus influenzae type b in 81 children between the ages of 6 and 7 years who attended the same primary school. The children’s health status was also monitored, without using antimicrobial treatment for healthy/asymptomatic carriers. Nasopharyngeal swabs were collected on 6 occasions during autumn months, from mid-September to mid-December 2016. The children who fell ill during the study were treated at the Ear, Nose and Throat Clinic, Sisters of Mercy University Hospital Center, Zagreb, Croatia.Results: Four hundred and sixty-three nasopharyngeal swabs were collected. Each child had at least one positive swab result. Bacterial colonization with Streptococcus pyogenes had the highest colonization rate. During the study, 83% of the children were healthy/asymptomatic carriers with no clinical signs of disease, while 17% became ill. The statistical results showed that the increase in all examined bacteria was statistically significant.Conclusions: Our study results showed that positive bacterial findings in nasopharyngeal swabs from clinically healthy carriers were not an indication for antibiotic therapy.