PT  - JOURNAL ARTICLE
AU  - Asseri, Ali A.
AU  - Zeng, Yi
AU  - Daines, Cori L.
TI  - Acute pulmonary embolism in a child with ANCA-negative idiopathic pulmonary capillaritis
AID  - 10.15537/smj.2019.6.24210
DP  - 2019 Jun 01
TA  - Saudi Medical Journal
PG  - 610--613
VI  - 40
IP  - 6
4099  - http://smj.org.sa/content/40/6/610.short
4100  - http://smj.org.sa/content/40/6/610.full
SO  - Saudi Med J2019 Jun 01; 40
AB  - Diffuse alveolar hemorrhage is an uncommon and often fatal condition in children that is characterized by distinct histopathological etiologies. Herein, we discuss the case of an 11-year-old girl who presented with acute worsening of hypoxia and left-sided chest pain. The patient had lung biopsy-proven idiopathic pulmonary capillaritis and was being treated with prednisolone every alternate day, azathioprine, and hydroxychloroquine. A contrast-computed tomography (CT) scan of the chest showed an acute left lower-lobe pulmonary embolism. Negative results were obtained on a test for thrombophilia. In children, pulmonary embolism with anti-neutrophil cytoplasmic antibody-negative idiopathic pulmonary capillaritis is a rare clinical condition. The exact cause of thrombus formation in this case is unknown; however, obesity, immobility, and chronic systemic corticosteroid therapy probably played a role.